Health
What Supplements Help With Weight Loss and How Do They Work?
Each of us has a unique fitness journey, but one thing stays true for everyone: a healthy diet and regular exercise are the cornerstones of successful weight management. However, in today’s fast-paced world, sticking to these good habits can often feel like an uphill battle. That’s where natural supplements can step in to lend a helping hand.
So, what supplements help with weight loss, and how do they work?
In this article, we’ll break down three top natural options, starting with PhenQ, and explain the essentials of effective, sustainable weight loss.
What Are the Best Supplements for Weight Loss?
The most effective weight loss supplements contain ingredients that enhance fat metabolism, suppress appetite, or increase energy. They shine when paired with a healthy diet and consistent exercise.
Consultation with a healthcare professional is crucial before taking supplements to ensure they align with your health needs and goals, providing a personalized approach to weight management.
Now, let’s check out three top supplements that can help with weight loss in 2025.
1. PhenQ
- Recommended by several clinicians on FrontrowMD
- 60-day money-back guarantee
- Get 15% off when you subscribe
- Free weight loss guide with every order
Cons
- May cause jitters if one is caffeine-sensitive
Overview
PhenQ is a comprehensive weight loss supplement created by Wolfson Brands (UK) Limited, a well-known company in the health and wellness industry. PhenQ aims to tackle weight loss from multiple angles, including burning stored fat, suppressing appetite, boosting energy, and improving mood.
Dosage
- 1 capsule with breakfast and one with lunch
- Avoid taking it after 3 pm, as caffeine may disrupt sleep
- If caffeine-sensitive, limit other caffeinated drinks while using PhenQ
Pricing
- 1-month supply: $69.99 or $59.49
- 3-month supply: $139.99 or $118.99
- 5-month supply: $209.99 or $178.49
User Testimonials
On the r/supplements subreddit, one user expressed they were “pretty impressed by PhenQ,” claiming it transformed their metabolism into a “fat-burning machine” after 4-5 weeks. In contrast, another Redditor reported no negative side effects but saw no significant weight loss, appetite reduction, or any other noticeable effects [1] [2].
2. KetoCharge
- Try risk-free for 2 months
- Bigger savings on higher packages
- Suitable for keto dieters
- Vegan friendly
Cons
- Limited formulation
Overview
By taking advantage of an effective weight loss diet plan, KetoCharge bolsters those on a keto diet by aiding the shift to ketosis, where fat is the main fuel. This consequently enhances weight loss and improves energy. It also aims to lessen keto flu effects and boost ketone levels.
Dosage
- 2 capsules upon waking with an 8-oz glass of water
Pricing
- 1-month supply: $59.499
- 3-month supply: $119.99
- 5-month supply: $179.99
User Testimonials
Alex on Trustpilot found it a “game-changer,” helping him enter and stay in ketosis faster, with boosted energy. Meanwhile, Barn reported not receiving a 3-month order after two months [3] [4].
3. Phen24
- Dual fat burner formula
- 60-day money-back guarantee
- Big savings on multi-buy packages
- Vegetarian and vegan-friendly
Cons
- Lacks essential vitamins
Overview
Phen24 stands out with its day-and-night formula, offering two types of pills for continuous weight loss support. It targets calorie burn, appetite suppression, and metabolism 24/7.
Dosage
- 1 capsule of the day formula each morning with breakfast
- 2 capsules of the night formula 15 minutes before your evening meal with 1-2 glasses of water
Pricing
- 1-month supply: $69.99
- 3-month supply: $139.99
- 5-month supply: $209.99
User Testimonials
On Trustpilot, a user enthusiastically claimed Phen24 “works wonders,” noting a significant improvement in metabolism and weight loss. However, Michael expressed extreme frustration with the delivery service, warning against expecting timely orders or any real assistance [5] [6].
Ingredients to Look for in the Best Supplements for Weight Loss
When considering weight loss supplements, it’s important to look for key ingredients that are extensively researched and shown to support weight loss. Here are some key ingredients to look for in top weight loss supplements:
- Caffeine: A natural stimulant found in many weight loss supplements, caffeine can help boost metabolism and increase energy expenditure, helping you burn calories [7].
- Green Tea Extract: Green tea extract, loaded with metabolism-boosting catechins, is a go-to for fat oxidation, hence its prevalence in dietary supplements.
- Glucomannan: A type of soluble fiber derived from the konjac plant, glucomannan may help promote feelings of fullness and reduce appetite, leading to reduced calorie intake.
- Conjugated Linoleic Acid (CLA): A fatty acid found in meat and dairy products, CLA promotes fat loss, especially in the abdominal area, and may help preserve lean muscle mass [8].
- Garcinia Cambogia: Garcinia cambogia, sourced from Garcinia gummi-gutta fruit rind, packs hydroxycitric acid (HCA), researched for its role in curbing fat production and appetite.
- Capsaicin: Capsaicin, the kick in chili peppers, amplifies metabolism and fuels fat-burning, which is why it’s in many weight loss formulas.
- Cayenne Pepper Extract: Similar to capsaicin, cayenne pepper extract contains compounds that can increase metabolism and promote fat oxidation, contributing to weight loss [9].
- 5-HTP: An amino acid precursor to serotonin, 5-HTP may help regulate appetite and reduce cravings, leading to decreased calorie intake and potential weight loss.
- Bitter Orange Extract: Also known as synephrine, the bitter orange extract has been studied for its potential to increase metabolism and promote fat loss, though it may have some cardiovascular risks associated with its use.
Role of Weight Loss Supplements
The role of supplements in weight loss can vary depending on the specific dietary supplement and individual factors. However, in general, supplements can play several roles in supporting weight loss efforts:
Enhancing Metabolism
Some metabolic boosters contain ingredients that increase metabolism and calorie burning, which may potentially facilitate weight loss. These ingredients can include caffeine, green tea extract, and capsicum extract.
Appetite Suppression
Certain supplements may help suppress appetite or reduce cravings, making adhering to a calorie-controlled diet easier and consuming fewer calories overall. Common ingredients such as glucomannan, chromium picolinate, and 5-HTP are used for appetite control.
Energy Boost
Many contain stimulants like caffeine or guarana extract, which can help increase energy levels and improve exercise performance. This can lead to more calories burned during physical activity, contributing to weight loss.
Promoting Fat Oxidation
Certain supplements are believed to enhance the body’s ability to burn fat for fuel, known as fat oxidation. Ingredients like L-carnitine, conjugated linoleic acid (CLA), and forskolin are often included in weight loss supplements for this purpose.
Addressing Nutrient Deficiencies
In some cases, nutrient deficiencies can interfere with weight loss efforts. So, what vitamins or supplements help with weight loss?
Nutrients that address specific deficiencies, such as vitamin D or magnesium, may help optimize metabolic function and support weight loss when deficiencies are present.
While not directly causing weight loss, maintaining adequate nutrient intake can support overall metabolic function and energy levels, which may indirectly contribute to weight management.
Understanding the Basics of Effective Weight Loss
Below are some of the effective ways to use weight loss supplements.
Consult with a Healthcare Professional
Before starting any weight loss supplement regimen, it’s crucial to consult with a healthcare professional or registered dietitian to ensure it’s safe and appropriate for your individual needs and health status.
Follow the Recommended Dosage
Adhere to the recommended dosage instructions provided on the supplement packaging or by your healthcare provider. Taking more than the recommended dose does not necessarily increase effectiveness and may pose health risks.
Combine Supplements With a Healthy Lifestyle
Weight loss supplements work best when used in conjunction with a balanced diet and regular exercise routine. They should not be viewed as a substitute for healthy lifestyle changes, but as a complement to support your efforts.
Stay Hydrated
Drink plenty of water throughout the day to help the body process and absorb the supplement’s ingredients effectively. Proper hydration also supports overall health and weight loss efforts.
Monitor for Side Effects
Pay attention to any potential side effects or adverse reactions while using weight loss supplements. If you experience negative symptoms, discontinue use and consult a healthcare professional.
Be Patient and Realistic
Weight loss supplements may take time to show noticeable results, and individual responses can vary. Set realistic goals and expectations, and be patient with your progress.
Cycle Usage if Necessary
Some weight loss supplements may require cycling on and off to prevent tolerance buildup or dependency. Follow all specific usage instructions provided by the manufacturer or your healthcare provider.
Combine With Other Strategies
Consider combining weight loss supplements with mindfulness practices, stress management techniques, and adequate sleep to optimize results and promote overall well-being.
By following these effective ways of using weight loss supplements, individuals can maximize their potential benefits while minimizing risks and achieving their weight loss goals safely and sustainably.
FAQs
Here are some common questions answered simply to help you understand what natural supplements help with weight loss.
Do Any Weight Loss Supplements Actually Work?
Yes, some weight loss supplements can genuinely help. The most effective ones work by supporting your body’s natural processes, such as boosting your metabolism, helping you feel fuller, or aiding fat burning. However, they work best when used alongside a healthy diet and regular exercise.
What Is the Best Supplement to Take for Weight Loss?
There isn’t one “best” supplement for everyone, as results depend on individual needs and body responses. However, commonly effective ingredients include green tea extract, caffeine, and fiber supplements. Products like PhenQ and Phen24 that combine these in well-researched doses are often considered top choices.
What Is the 30/30/30 Rule for Weight Loss?
It suggests eating 30 grams of protein within 30 minutes of waking up, followed by 30 minutes of low-intensity exercise. The idea is that this combination can help control appetite, boost metabolism, and encourage fat-burning throughout the day.
Which Vitamin Helps Lose Belly Fat?
Certain vitamins like B, C, and D support overall metabolic health, which can contribute to reducing overall body fat, including around the belly.
Final Thoughts on Weight Loss Supplements
We hope this guide has shed light on what supplements can help with weight loss and how they can support your journey. While healthy eating and consistent exercise remain the foundation, incorporating the right natural supplements can truly make the path less daunting.
PhenQ is our overall best option, but those on a keto diet may prefer KetoCharge. That said, Phen24 might seem like a better pick if you struggle with cravings in the evening and fatigue in the morning.
By choosing the right product for your needs and maintaining these core habits, you’re well on your way to achieving your weight loss goals and feeling your best.
References
- dhanusat. “Best Fat Burner Supplement Products?” Reddit.com, https://www.reddit.com/r/Supplements/comments/1gda259/comment/lu94cu3/. Accessed 8 July 2025.
- dhanusat. “Best Fat Burner Supplement Products?” Reddit.com, https://www.reddit.com/r/Supplements/comments/1gda259/comment/mldu5vk/. Accessed 8 July 2025.
- “Alex Fry Gave Keto Charge 【Official & Deals ✔️✔️✔️ 】 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/660f065db2ec54c33a65d0f3. Accessed 8 July 2025.
- “Barn Reeds Gave Keto Charge 【Official & Deals ✔️✔️✔️ 】 1 Star. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/66e0b5ee30443c4fefa44df0. Accessed 8 July 2025.
- “Anonymous Gave Phen24 Fat Burner Diet 5 Stars. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/67e135f18c7bffab1a440376. Accessed 8 July 2025.
- “Michael Sitton Gave Phen24 Fat Burner Diet 1 Star. Check out the Full Review.” Trustpilot, https://www.trustpilot.com/reviews/67545de49aec7cef944f1c70. Accessed 8 July 2025.
- Tabrizi, Reza, et al. “The Effects of Caffeine Intake on Weight Loss: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.” Critical Reviews in Food Science and Nutrition, vol. 59, no. 16, 2019, pp. 2688–2696, doi:10.1080/10408398.2018.1507996.
- Whigham, Leah D., et al. “Efficacy of Conjugated Linoleic Acid for Reducing Fat Mass: A Meta-Analysis in Humans.” The American Journal of Clinical Nutrition, vol. 85, no. 5, 2007, pp. 1203–1211, doi:10.1093/ajcn/85.5.1203.
- Zheng, Jia, et al. “Dietary Capsaicin and Its Anti-Obesity Potency: From Mechanism to Clinical Implications.” Bioscience Reports, vol. 37, no. 3, 2017, p. BSR20170286, doi:10.1042/BSR20170286.
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